When it comes to Botox injections, it takes some swelling to smooth up the wrinkles. While most of the swelling goes away two days after the injections, some swelling does stay until Botox is fully flushed out of the muscle tissue by the blood cells. It's that minor swelling that gives Botox patients younger, "rounded" face look. Swelling is the body's natural reaction to Botox (Botulinum toxin) which is the most toxic protein known to mankind.
Photoshop how celebrities (or politicians) would look if they used higher doses of Botox and had round swelled up faces. Let this contest be a "public warning to Hollywood", which is obsessed with Botox these days.